A/Prof David van der Poorten
Dr Roslyn Vongsuvanh
  Prof Golo Ahlenstiel
Dr Way Siow

Appointments & Enquiries:  (02) 8711 0160

Helicobacter Treatment

Helicobacter pylori diagram 

Helicobacter Pylori

Helicobacter Pylori ulcer diagram

Ulcer Diagram

 Stains

Helicobacter Pylori

Helicobacter Pylori is a spiral shaped bacteria that is now established as a significant cause of Gastritis, Peptic Ulcer disease, Gastric cancer and rare forms of gastric lymphoma (MALT). It is often associated with dyspeptic symptoms (upper abdominal discomfort, bloating and nausea) and can be a cause of bad breath (halitosis). Detailed information on Helicobacter can be found here (Link to the detailed stuff below).

Helicobacter can be difficult to eradicate with first line antibiotic regimens only effective 65-85% of the time. Repeated courses of the same therapy rarely work. Having had an active interest in Helicobacter Pylori treatment since my training, I offer evidence based eradication strategies based on the safest and most effective current treatments.

 

Specialised Services Provided

Effective Helicobacter eradication therapy:

  • Levofloxacin triple therapy
  • Rifabutin triple therapy
  • Bismuth based quadruple therapy
  • Novel tailored regimens
  • Treatments for patients with penicillin allergy including arrangement of penicillin allergy testing when appropriate
  • Endoscopy to look for and monitor complications of infection

 

Quick Case Study

A 40 year old woman came to see me in 2009 with Helicobacter infection refractory to two courses of first line therapy. She had been diagnosed on a Urease breath test to investigate symptoms of bloating and burning epigastric pain with a background family history of stomach cancer. Her initial treatments were with metronidazole (flagyl) substituted for amoxicillin due to a remote history of penicillin allergy. At endoscopy I found moderate active gastritis with plentiful helicobacter organisms. I treated her with a bismuth based quadruple therapy that did not contain penicillin, but unfortunately this was unsuccessful. Because the majority of other treatments require amoxicillin, I arranged for penicillin allergy testing through Westmead hospital, which ultimately showed that she did not have a true allergy. I treated her with Rifabutin triple therapy and the Helicobcater was eradicated.

 

 

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